Fully autonomous vehicles and robotic surgery machines have enormous potential to change society However the combination of safety security & privacy of connected and automated systems is still a concern in multiple application domains for many consumers in Europe. As the trust to adopt these technologies is not yet here for many potential users, the industry and research communities need to work on an answer to ensure that these concerns are no longer roadblocks for further evolution in the transport and medical sectors. The high-level goal of SECREDAS is to develop software for validating architecting methodologies, reference architectures, components and suitable integration, as well as verification approaches for automated systems in different domains. These will combine high security and privacy protection while preserving functional-safety and operational performance. SECREDAS will take a first important step to developing and enhancing trustworthiness, particularly for the future European transportation and medical industries. This will help to make connected and automated vehicles a reality, and ensure that European Original Equipment Manufactures (OEM) remain competitive and can maintain their world leading position. In addition, SECREDAS addresses cross-domain cybersecurity and safety related technologies in the areas of automated systems in the medical, railway & aerospace sectors, as well as support cross-domain actions. Within SECREDAS, a number of relevant user scenarios with specific requirements of safety security and privacy will be studied in detail. Together with current state-of-the-art reference architectures, the user scenarios will lead to a next generation of reference architectures and common elements for multiple application domains, supported by tooling incorporating design and development methodologies. On top of common generic elements to safeguard safety, security & privacy, a number of domain-specific solutions will be designed. With the inclusion of the automotive sector in particular, and the addition of the medical, railway and aerospace spin-outs, SECREDAS will enable a wide application of its results. SECREDAS brings together a consortium with partners from 15 different countries, covering the whole automotive value chain (OEMs, TIER1’s, TIER2’s), key players in the medical area, a number of players in other transport domains (railways, aerospace) and key research institutes in order to tackle the objectives in a balanced way between generic common offerings and domain-specific solutions.